Oncogenicity of infectious canine hepatitis virus in hamsters.

Characteristics in tissue culture of infectious canine hepatitis virus-induced hamster tumor cells.

In a preeeding paper, we demonstrated the oncogenicity of the infectious canine hepatitis (ICH) virus in newborn hamsters (KINJo et al., 1968). Although neither the primary tumors induced in hamsters by the ICH virus or the transplanted tumors contained dernonstrable infectious virus, they did, however contain an ICH virus specific tumor antigen. Also the tumor-bearing animals developed complem...

In vitro transformation of hamster cells by infectious canine hepatitis virus.

Persistent West Nile virus infection in the golden hamster: studies on its mechanism and possible implications for other flavivirus infections.

Golden hamsters (Mesocricetus auratus) experimentally infected with West Nile virus (WNV) developed chronic renal infection and persistent shedding of virus in urine for up to 8 months, despite initial rapid clearance of virus from blood and the timely appearance of high levels of specific neutralizing antibodies. Infectious WNV could be recovered by direct culture of their urine and by coculti...

Humanized monoclonal antibody against West Nile virus envelope protein administered after neuronal infection protects against lethal encephalitis in hamsters.

Humans infected with West Nile virus (WNV) may clinically present with symptoms that are suggestive of neurological infection. Nearly all treatments of WNV disease have been effective in animal models only if administered before or soon after viral challenge. Here, we evaluated whether a potent neutralizing anti-WNV humanized monoclonal antibody (MAb), hE16, could improve the course of disease ...

Properties of a Small Virus Associated with Infectious Canine Hepatitis Virus